Table 1

Patients with MDD using TCA and SSRI medication where Cohen's d reflects the difference between treatment and contrast condition.
Measure
 Heart Rate
 SDNN
 SDANN
 RMSSD
 LF
 LnHF
 HF
 LF/HF
 CV
 pNN50
Units
 bpm
 ms
 ms
 ms2
 ms2
 ms2
 ms2
 ratio
 ratio
 percent
TCAs – short (2–10 minute) supine









Mean Baseline Value
 75.91
 32.28
21.60
5.80
 0.51
4.07
Mean Percent Change
 20.8%
 -62.9%
-67.3%
-35.5%
 -79.4%
-55.2%
Number of Comparisons
 8
 8
6
2
 4
8
Mean Effect Size
 4.83
 -2.43
-3.34
-4.54
 -0.96
-5.52
t
 7.53*
 9.32*
7.79*
2.40
 5.85*
4.17*
p
 0.00
 0.00
0.00
0.25
 0.01
0.00
TCAs 24 hour ambulatory









Mean Baseline Value
 82.60
 115.85
 106.7
 31.00




10.00
Mean Percent Change
 7.5%
 -16.1%
 -3.7%
 -12.9%




-30.0%
Number of Comparisons
 1
 2
 2
 1




1
Mean Effect Size
 1.98
 -0.20
 0.31
 -2.71




-3.34
t
0.10
 0.10






p
0.94
 0.94






SSRIs – short (2–10 minute) supine









Mean Baseline Value
 76.00
 28.67
 26.375
 26.38
5.60
 0.507
3.60
Mean Percent Change
 -2.0%
 1.0%
-2.4%
-1.4%
 -14.8%
-1.9%
Number of Comparisons
 4
 3
4
1
 1
3
Mean Effect Size
 -0.63
 0.06
1.42
-0.15
 -0.26
-0.26
t
 6.33*
 3.46**
0.54



2.71
p
 0.01
 0.07
0.63



0.11
SSRIs 24 hour ambulatory









Mean Baseline Value
 81.30
 30.08
 118.1
 30.00




9.00
Mean Percent Change
 -0.5%
 1.7%
 0.0%
 16.7%




33.3%
Number of Comparisons
 1
 2
 2
 1




1
Mean Effect Size
 -0.10
 0.51
 0.43
 1.76




1.76
t
0.30
 0.41






p
0.82
 0.75






Two studies used 24 hour monitoring. Only studies have been included where effects of specific drugs could be evaluated. Negative values indicate decreases in the parameter with treatment, positive values indicate increases. (* indicates p < .05, ** indicates p < .10)

van Zyl et al. BioPsychoSocial Medicine 2008 2:12   doi:10.1186/1751-0759-2-12
Open Data