Table 1

Functional states associated with vmPFC-activity

Increased activity:

Decreased activity:

Rest, sleep

Low intense motor activity

Elevated parasympathetic activity

Posttraumatic stress disorder

Lowered sympathetic activity

Depressive Disorder

Suppression of negative emotional signal

Extinction of previously fearfully conditioned stimuli

Controllability over stressful situation

Hänsel and von Känel BioPsychoSocial Medicine 2008 2:21   doi:10.1186/1751-0759-2-21